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CD27 Promotes Survival of Activated T Cells and Complements CD28 in Generation and Establishment of the Effector T Cell Pool

CD27, like CD28, acts in concert with the T cell receptor to support T cell expansion. Using CD27(−/−) mice, we have shown earlier that CD27 determines the magnitude of primary and memory T cell responses to influenza virus. Here, we have examined the relative contributions of CD27 and CD28 to gener...

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Detalles Bibliográficos
Autores principales: Hendriks, Jenny, Xiao, Yanling, Borst, Jannie
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194245/
https://www.ncbi.nlm.nih.gov/pubmed/14581610
http://dx.doi.org/10.1084/jem.20030916