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Essential Role for the C5a Receptor in Regulating the Effector Phase of Synovial Infiltration and Joint Destruction in Experimental Arthritis

A characteristic feature of rheumatoid arthritis is the abundance of inflammatory cells in the diseased joint. Two major components of this infiltrate are neutrophils in the synovial fluid and macrophages in the synovial tissue. These cells produce cytokines including tumor necrosis factor α and oth...

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Detalles Bibliográficos
Autores principales: Grant, Ethan P., Picarella, Dominic, Burwell, Timothy, Delaney, Tracy, Croci, Alisa, Avitahl, Nicole, Humbles, Alison A., Gutierrez-Ramos, Jose-Carlos, Briskin, Michael, Gerard, Craig, Coyle, Anthony J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194257/
https://www.ncbi.nlm.nih.gov/pubmed/12461081
http://dx.doi.org/10.1084/jem.20020205