Telomerase Activation and Rejuvenation of Telomere Length in Stimulated T Cells Derived from Serially Transplanted Hematopoietic Stem Cells

Telomeres shorten in hematopoietic cells, including hematopoietic stem cells (HSCs), during aging and after transplantation, despite the presence of readily detectable levels of telomerase in these cells. In T cells, antigenic stimulation has been shown to result in a marked increase in the level of...

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Detalles Bibliográficos
Autores principales: Allsopp, Richard C., Cheshier, Samuel, Weissman, Irving L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194261/
https://www.ncbi.nlm.nih.gov/pubmed/12461078
http://dx.doi.org/10.1084/jem.20021003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194261/
https://www.ncbi.nlm.nih.gov/pubmed/12461078
http://dx.doi.org/10.1084/jem.20021003

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