Correction of the Iron Overload Defect in β-2-Microglobulin Knockout Mice by Lactoferrin Abolishes Their Increased Susceptibility to Tuberculosis

As a resident of early endosomal phagosomes, Mycobacterium tuberculosis is connected to the iron uptake system of the host macrophage. β-2-microglobulin (β2m) knockout (KO) mice are more susceptible to tuberculosis than wild-type mice, which is generally taken as a proof for the role of major histoc...

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Detalles Bibliográficos
Autores principales: Schaible, Ulrich E., Collins, Helen L., Priem, Friedrich, Kaufmann, Stefan H.E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194267/
https://www.ncbi.nlm.nih.gov/pubmed/12461085
http://dx.doi.org/10.1084/jem.20020897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194267/
https://www.ncbi.nlm.nih.gov/pubmed/12461085
http://dx.doi.org/10.1084/jem.20020897

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