DNA-dependent Protein Kinase Activity Is Not Required for Immunoglobulin Class Switching

Class switch recombination (CSR), similar to V(D)J recombination, is thought to involve DNA double strand breaks and repair by the nonhomologous end–joining pathway. A key component of this pathway is DNA-dependent protein kinase (DNA-PK), consisting of a catalytic subunit (DNA-PKcs) and a DNA-bindi...

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Detalles Bibliográficos
Autores principales: Bosma, Gayle C., Kim, Jiyoon, Urich, Teresa, Fath, Donna M., Cotticelli, Maria G., Ruetsch, Norman R., Radic, Marko Z., Bosma, Melvin J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194268/
https://www.ncbi.nlm.nih.gov/pubmed/12461083
http://dx.doi.org/10.1084/jem.20001871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194268/
https://www.ncbi.nlm.nih.gov/pubmed/12461083
http://dx.doi.org/10.1084/jem.20001871

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