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Structure of Arabidopsis thaliana 5-methylthioribose kinase reveals a more occluded active site than its bacterial homolog

BACKGROUND: Metabolic variations exist between the methionine salvage pathway of humans and a number of plants and microbial pathogens. 5-Methylthioribose (MTR) kinase is a key enzyme required for methionine salvage in plants and many bacteria. The absence of a mammalian homolog suggests that MTR ki...

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Detalles Bibliográficos
Autores principales: Ku, Shao-Yang, Cornell, Kenneth A, Howell, P Lynne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194712/
https://www.ncbi.nlm.nih.gov/pubmed/17961230
http://dx.doi.org/10.1186/1472-6807-7-70