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Antiretroviral Pre-exposure Prophylaxis Prevents Vaginal Transmission of HIV-1 in Humanized BLT Mice

BACKGROUND: Worldwide, vaginal transmission now accounts for more than half of newly acquired HIV-1 infections. Despite the urgency to develop and implement novel approaches capable of preventing HIV transmission, this process has been hindered by the lack of adequate small animal models for preclin...

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Detalles Bibliográficos
Autores principales: Denton, Paul W, Estes, Jacob D, Sun, Zhifeng, Othieno, Florence A, Wei, Bangdong L, Wege, Anja K, Powell, Daniel A, Payne, Deborah, Haase, Ashley T, Garcia, J. Victor
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194746/
https://www.ncbi.nlm.nih.gov/pubmed/18198941
http://dx.doi.org/10.1371/journal.pmed.0050016