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Frame disruptions in human mRNA transcripts, and their relationship with splicing and protein structures

BACKGROUND: Efforts to gather genomic evidence for the processes of gene evolution are ongoing, and are closely coupled to improved gene annotation methods. Such annotation is complicated by the occurrence of disrupted mRNAs (dmRNAs), harbouring frameshifts and premature stop codons, which can be co...

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Detalles Bibliográficos
Autores principales: Harrison, Paul, Yu, Zhan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194788/
https://www.ncbi.nlm.nih.gov/pubmed/17937804
http://dx.doi.org/10.1186/1471-2164-8-371