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Frame disruptions in human mRNA transcripts, and their relationship with splicing and protein structures
BACKGROUND: Efforts to gather genomic evidence for the processes of gene evolution are ongoing, and are closely coupled to improved gene annotation methods. Such annotation is complicated by the occurrence of disrupted mRNAs (dmRNAs), harbouring frameshifts and premature stop codons, which can be co...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194788/ https://www.ncbi.nlm.nih.gov/pubmed/17937804 http://dx.doi.org/10.1186/1471-2164-8-371 |