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Statistical power of phylo-HMM for evolutionarily conserved element detection

BACKGROUND: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conserved elements based on multiple genome alignments, but the method has not been rigorously evaluated. RESULTS: We report h...

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Detalles Bibliográficos
Autores principales: Fan, Xiaodan, Zhu, Jun, Schadt, Eric E, Liu, Jun S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194792/
https://www.ncbi.nlm.nih.gov/pubmed/17919331
http://dx.doi.org/10.1186/1471-2105-8-374