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Statistical power of phylo-HMM for evolutionarily conserved element detection
BACKGROUND: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conserved elements based on multiple genome alignments, but the method has not been rigorously evaluated. RESULTS: We report h...
Autores principales: | Fan, Xiaodan, Zhu, Jun, Schadt, Eric E, Liu, Jun S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194792/ https://www.ncbi.nlm.nih.gov/pubmed/17919331 http://dx.doi.org/10.1186/1471-2105-8-374 |
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