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Taxol Crystals Can Masquerade as Stabilized Microtubules

Taxol is a potent anti-mitotic drug used in chemotherapy, angioplastic stents, and cell biology research. By binding and stabilizing microtubules, Taxol inhibits their dynamics, crucial for cell division, motility, and survival. The drug has also been reported to induce formation of asters and bundl...

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Detalles Bibliográficos
Autores principales: Foss, Margit, Wilcox, Buck W. L., Alsop, G. Bradley, Zhang, Dahong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194920/
https://www.ncbi.nlm.nih.gov/pubmed/18213384
http://dx.doi.org/10.1371/journal.pone.0001476