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Taxol Crystals Can Masquerade as Stabilized Microtubules
Taxol is a potent anti-mitotic drug used in chemotherapy, angioplastic stents, and cell biology research. By binding and stabilizing microtubules, Taxol inhibits their dynamics, crucial for cell division, motility, and survival. The drug has also been reported to induce formation of asters and bundl...
Autores principales: | Foss, Margit, Wilcox, Buck W. L., Alsop, G. Bradley, Zhang, Dahong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194920/ https://www.ncbi.nlm.nih.gov/pubmed/18213384 http://dx.doi.org/10.1371/journal.pone.0001476 |
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