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Dependence of T Cell Antigen Recognition on the Dimensions of an Accessory Receptor–Ligand Complex

The T cell antigen receptor (TCR) and its ligand peptide–major histocompatibility complex (MHC) are small (∼7 nm) compared with other abundant cell surface molecules such as integrins, CD43, and CD45 (23–50 nm). We have proposed that molecules at the T cell/antigen-presenting cell (APC) interface se...

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Detalles Bibliográficos
Autores principales: Wild, Martin K., Cambiaggi, Anna, Brown, Marion H., Davies, Elizabeth A., Ohno, Hiroshi, Saito, Takashi, van der Merwe, P. Anton
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195552/
https://www.ncbi.nlm.nih.gov/pubmed/10429668