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Dependence of T Cell Antigen Recognition on the Dimensions of an Accessory Receptor–Ligand Complex
The T cell antigen receptor (TCR) and its ligand peptide–major histocompatibility complex (MHC) are small (∼7 nm) compared with other abundant cell surface molecules such as integrins, CD43, and CD45 (23–50 nm). We have proposed that molecules at the T cell/antigen-presenting cell (APC) interface se...
Autores principales: | Wild, Martin K., Cambiaggi, Anna, Brown, Marion H., Davies, Elizabeth A., Ohno, Hiroshi, Saito, Takashi, van der Merwe, P. Anton |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195552/ https://www.ncbi.nlm.nih.gov/pubmed/10429668 |
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