Different Mismatch Repair Deficiencies All Have the Same Effects on Somatic Hypermutation: Intact Primary Mechanism Accompanied by Secondary Modifications

Somatic hypermutation of Ig genes is probably dependent on transcription of the target gene via a mutator factor associated with the RNA polymerase (Storb, U., E.L. Klotz, J. Hackett, Jr., K. Kage, G. Bozek, and T.E. Martin. 1998. J. Exp. Med. 188:689–698). It is also probable that some form of DNA...

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Detalles Bibliográficos
Autores principales: Kim, Nayun, Bozek, Grazyna, Lo, James C., Storb, Ursula
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195558/
https://www.ncbi.nlm.nih.gov/pubmed/10429667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195558/
https://www.ncbi.nlm.nih.gov/pubmed/10429667

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