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Anergy and Cytokine-Mediated Suppression as Distinct Superantigen-Induced Tolerance Mechanisms in Vivo
Recombinant-activating gene 2 (RAG-2(−/−)) T cell receptor–transgenic mice repeatedly injected with the superantigen staphylococcal enterotoxin A entered a tolerant state in which splenic CD4(+) T cells produced little interleukin (IL)-2, interferon γ, or IL-4. This state resulted from a combination...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1999
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195559/ https://www.ncbi.nlm.nih.gov/pubmed/10429670 |