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Targeted Inhibition of Intrinsic Coagulation Limits Cerebral Injury in Stroke without Increasing Intracerebral Hemorrhage

Agents that restore vascular patency in stroke also increase the risk of intracerebral hemorrhage (ICH). As Factor IXa is a key intermediary in the intrinsic pathway of coagulation, targeted inhibition of Factor IXa–dependent coagulation might inhibit microvascular thrombosis in stroke without impai...

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Detalles Bibliográficos
Autores principales: Choudhri, Tanvir F., Hoh, Brian L., Prestigiacomo, Charles J., Huang, Judy, Kim, Louis J., Schmidt, Ann Marie, Kisiel, Walter, Connolly, E. Sander, Pinsky, David J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195562/
https://www.ncbi.nlm.nih.gov/pubmed/10429673