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Targeted Inhibition of Intrinsic Coagulation Limits Cerebral Injury in Stroke without Increasing Intracerebral Hemorrhage
Agents that restore vascular patency in stroke also increase the risk of intracerebral hemorrhage (ICH). As Factor IXa is a key intermediary in the intrinsic pathway of coagulation, targeted inhibition of Factor IXa–dependent coagulation might inhibit microvascular thrombosis in stroke without impai...
Autores principales: | Choudhri, Tanvir F., Hoh, Brian L., Prestigiacomo, Charles J., Huang, Judy, Kim, Louis J., Schmidt, Ann Marie, Kisiel, Walter, Connolly, E. Sander, Pinsky, David J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195562/ https://www.ncbi.nlm.nih.gov/pubmed/10429673 |
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