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Molecular Mimicry of Human Cytochrome P450 by Hepatitis C Virus at the Level of Cytotoxic T Cell Recognition

Hepatitis C virus (HCV) is thought to be involved in the pathogenesis of autoimmune hepatitis (AIH) type 2, which is defined by the presence of type I antiliver kidney microsome autoantibodies directed mainly against cytochrome P450 (CYP)2D6 and by autoreactive liver infiltrating T cells. Virus-spec...

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Detalles Bibliográficos
Autores principales: Kammer, Andreas R., van der Burg, Sjoerd H., Grabscheid, Benno, Hunziker, Isabelle P., Kwappenberg, Kitty M.C., Reichen, Jürg, Melief, Cornelis J.M., Cerny, Andreas
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195568/
https://www.ncbi.nlm.nih.gov/pubmed/10432280