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Telomere Fluorescence Measurements in Granulocytes and T Lymphocyte Subsets Point to a High Turnover of Hematopoietic Stem Cells and Memory T Cells in Early Childhood

To study telomere length dynamics in hematopoietic cells with age, we analyzed the average length of telomere repeat sequences in diverse populations of nucleated blood cells. More than 500 individuals ranging in age from 0 to 90 yr, including 36 pairs of monozygous and dizygotic twins, were analyze...

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Detalles Bibliográficos
Autores principales: Rufer, Nathalie, Brümmendorf, Tim H., Kolvraa, Steen, Bischoff, Claus, Christensen, Kaare, Wadsworth, Louis, Schulzer, Michael, Lansdorp, Peter M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195579/
https://www.ncbi.nlm.nih.gov/pubmed/10432279