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Endothelial-Monocyte Activating Polypeptide Ii, a Novel Antitumor Cytokine That Suppresses Primary and Metastatic Tumor Growth and Induces Apoptosis in Growing Endothelial Cells

Neovascularization is essential for growth and spread of primary and metastatic tumors. We have identified a novel cytokine, endothelial-monocyte activating polypeptide (EMAP) II, that potently inhibits tumor growth, and appears to have antiangiogenic activity. Mice implanted with Matrigel showed an...

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Detalles Bibliográficos
Autores principales: Schwarz, Margaret A., Kandel, Jessica, Brett, Jerald, Li, Jun, Hayward, Joanne, Schwarz, Roderich E., Chappey, Olivier, Wautier, Jean-Luc, Chabot, John, Gerfo, Paul Lo, Stern, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195582/
https://www.ncbi.nlm.nih.gov/pubmed/10430623