Reduced Isotype Switching in Splenic B Cells from Mice Deficient in Mismatch Repair Enzymes

Mice deficient in various mismatch repair (MMR) enzymes were examined to determine whether this repair pathway is involved in antibody class switch recombination. Splenic B cells from mice deficient in Msh2, Mlh1, Pms2, or Mlh1 and Pms2 were stimulated in culture with lipopolysaccharide (LPS) to ind...

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Detalles Bibliográficos
Autores principales: Schrader, Carol E., Edelmann, Winfried, Kucherlapati, Raju, Stavnezer, Janet
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195591/
https://www.ncbi.nlm.nih.gov/pubmed/10430621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195591/
https://www.ncbi.nlm.nih.gov/pubmed/10430621

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