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B Cell Antigen Receptor Specificity and Surface Density Together Determine B-1 versus B-2 Cell Development

Mice expressing the immunoglobulin (Ig) heavy (H) chain variable (V) region from a rearranged V(H)12 gene inserted into the IgH locus generate predominantly B-1 cells, whereas expression of two other V(H) region transgenes (V(H)B1-8 and V(H)glD42) leads to the almost exclusive generation of conventi...

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Detalles Bibliográficos
Autores principales: Lam, Kong-Peng, Rajewsky, Klaus
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195595/
https://www.ncbi.nlm.nih.gov/pubmed/10449518