Expression Levels of B Cell Surface Immunoglobulin Regulate Efficiency of Allelic Exclusion and Size of Autoreactive B-1 Cell Compartment

Surface-expressed immunoglobulin (Ig) has been shown to have a critical role in allelic exclusion of Ig heavy (H) and light (L) chains. Although various degrees of suppression of endogenous Ig expression are observed in Ig transgenic (Tg) mice, it was not clear whether this difference is due to diff...

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Detalles Bibliográficos
Autores principales: Watanabe, Norihiko, Nisitani, Sazuku, Ikuta, Koichi, Suzuki, Misao, Chiba, Tsutomu, Honjo, Tasuku
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195600/
https://www.ncbi.nlm.nih.gov/pubmed/10449517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195600/
https://www.ncbi.nlm.nih.gov/pubmed/10449517

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