Alteration of Interleukin 4 Production Results in the Inhibition of T Helper Type 2 Cell–Dominated Inflammatory Bowel Disease in T Cell Receptor α Chain–Deficient Mice

T cell receptor α chain–deficient (TCR-α(−/−)) mice are known to spontaneously develop inflammatory bowel disease (IBD). The colitis that develops in these mice is associated with increased numbers of T helper cell (Th)2-type CD4(+)TCR-ββ (CD4(+)ββ) T cells producing predominantly interleukin (IL)-4...

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Detalles Bibliográficos
Autores principales: Iijima, Hideki, Takahashi, Ichiro, Kishi, Daisuke, Kim, Jin-Kyung, Kawano, Sunao, Hori, Masatsugu, Kiyono, Hiroshi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195615/
https://www.ncbi.nlm.nih.gov/pubmed/10477546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195615/
https://www.ncbi.nlm.nih.gov/pubmed/10477546

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