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The Final Maturation of at Least Some Single-Positive Cd4(hi)Thymocytes Does Not Require T Cell Receptor–Major Histocompatibility Complex Contact
The majority (∼70%) of postselection CD4(+) single-positive (SP) thymocytes are CD8(lo)CD4(hi). These cells express very low levels of CD8, undetectable by flow cytofluorimetric (FCM) analysis, but sufficiently high to allow purification by panning. Unlike the fully mature CD8(−)CD4(hi) thymocytes,...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1999
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195626/ https://www.ncbi.nlm.nih.gov/pubmed/10499914 |