Receptor Avidity and Costimulation Specify the Intracellular Ca(2+) Signaling Pattern in Cd4(+)Cd8(+) Thymocytes

Thymocyte maturation is governed by antigen–T cell receptor (TCR) affinity and the extent of TCR aggregation. Signals provided by coactivating molecules such as CD4 and CD28 also influence the fate of immature thymocytes. The mechanism by which differences in antigen–TCR avidity encode unique matura...

Descripción completa

Detalles Bibliográficos
Autores principales: Freedman, Bruce D., Liu, Qing-Hua, Somersan, Selin, Kotlikoff, Michael I., Punt, Jennifer A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195644/
https://www.ncbi.nlm.nih.gov/pubmed/10510084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195644/
https://www.ncbi.nlm.nih.gov/pubmed/10510084

Ejemplares similares