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An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation

A T helper cell type 1–mediated colitis develops in severe combined immunodeficient mice after transfer of CD45RB(high) CD4(+) T cells and can be prevented by cotransfer of the CD45RB(low) subset. The immune-suppressive activities of the CD45RB(low) T cell population can be reversed in vivo by admin...

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Detalles Bibliográficos
Autores principales: Asseman, Chrystelle, Mauze, Smita, Leach, Michael W., Coffman, Robert L., Powrie, Fiona
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195650/
https://www.ncbi.nlm.nih.gov/pubmed/10510089