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Immunoglobulin A1 Protease, an Exoenzyme of Pathogenic Neisseriae, Is a Potent Inducer of Proinflammatory Cytokines

A characteristic of human pathogenic Neisseriae is the production and secretion of an immunoglobulin (Ig)A1-specific serine protease (IgA1 protease) that cleaves preferentially human IgA1 and other target proteins. Here we show a novel function for native IgA1 protease, i.e., the induction of proinf...

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Detalles Bibliográficos
Autores principales: Lorenzen, Dirk R., Düx, Frank, Wölk, Uwe, Tsirpouchtsidis, Anastasios, Haas, Gaby, Meyer, Thomas F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195656/
https://www.ncbi.nlm.nih.gov/pubmed/10523603