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Txk, a Nonreceptor Tyrosine Kinase of the Tec Family, Is Expressed in T Helper Type 1 Cells and Regulates Interferon γ Production in Human T Lymphocytes

Differentiation of human T cells into T helper (Th)1 and Th2 cells is vital for the development of cell-mediated and humoral immunity, respectively. However, the precise mechanism responsible for the Th1 cell differentiation is not fully clarified. We have studied the expression and function of Txk,...

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Detalles Bibliográficos
Autores principales: Kashiwakura, Jun-ichi, Suzuki, Noboru, Nagafuchi, Hiroko, Takeno, Mitsuhiro, Takeba, Yuko, Shimoyama, Yoshihiro, Sakane, Tsuyoshi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195662/
https://www.ncbi.nlm.nih.gov/pubmed/10523612