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Binding and Antigen Presentation of Ceramide-Containing Glycolipids by Soluble Mouse and Human Cd1d Molecules

We have purified soluble mouse and human CD1d molecules to assess the structural requirements for lipid antigen presentation by CD1. Plate-bound CD1d molecules from either species can present the glycolipid α-galactosyl ceramide (α-GalCer) to mouse natural killer T cells, formally demonstrating both...

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Detalles Bibliográficos
Autores principales: Naidenko, Olga V., Maher, Juli K., Ernst, William A., Sakai, Teruyuki, Modlin, Robert L., Kronenberg, Mitchell
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195664/
https://www.ncbi.nlm.nih.gov/pubmed/10523605