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Impaired Nk1.1 T Cell Development in Mice Transgenic for a T Cell Receptor β Chain Lacking the Large, Solvent-Exposed Cβ Fg Loop

A striking feature of the T cell receptor (TCR) β chain structure is the large FG loop that protrudes freely into the solvent on the external face of the Cβ domain. We have already shown that a transgene-encoded Vβ8.2(+) TCR β chain lacking the complete Cβ FG loop supports normal development and fun...

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Detalles Bibliográficos
Autores principales: Degermann, Sylvie, Sollami, Giuseppina, Karjalainen, Klaus
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195682/
https://www.ncbi.nlm.nih.gov/pubmed/10544207