Inhibition of Interleukin 2 Signaling and Signal Transducer and Activator of Transcription (Stat)5 Activation during T Cell Receptor–Mediated Feedback Inhibition of T Cell Expansion

Limitation of clonal expansion of activated T cells is necessary for immune homeostasis, and is achieved by growth arrest and apoptosis. Growth arrest and apoptosis can occur passively secondary to cytokine withdrawal, or can be actively induced by religation of the T cell receptor (TCR) in previous...

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Detalles Bibliográficos
Autores principales: Lee, In-Hong, Li, Wai Ping, Hisert, Katherine B., Ivashkiv, Lionel B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195684/
https://www.ncbi.nlm.nih.gov/pubmed/10544198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195684/
https://www.ncbi.nlm.nih.gov/pubmed/10544198

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