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Caspase Activation Is Required for T Cell Proliferation

Triggering of Fas (CD95) by its ligand (FasL) rapidly induces cell death via recruitment of the adaptor protein Fas-associated death domain (FADD), resulting in activation of a caspase cascade. It was thus surprising that T lymphocytes deficient in FADD were reported recently to be not only resistan...

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Detalles Bibliográficos
Autores principales: Kennedy, Norman J., Kataoka, Takao, Tschopp, Jürg, Budd, Ralph C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195711/
https://www.ncbi.nlm.nih.gov/pubmed/10601363