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Caspase Activation Is Required for T Cell Proliferation
Triggering of Fas (CD95) by its ligand (FasL) rapidly induces cell death via recruitment of the adaptor protein Fas-associated death domain (FADD), resulting in activation of a caspase cascade. It was thus surprising that T lymphocytes deficient in FADD were reported recently to be not only resistan...
Autores principales: | Kennedy, Norman J., Kataoka, Takao, Tschopp, Jürg, Budd, Ralph C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195711/ https://www.ncbi.nlm.nih.gov/pubmed/10601363 |
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