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Monocyte Chemoattractant Protein 1–Dependent Leukocytic Infiltrates Are Responsible for Autoimmune Disease in Mrl-Fas(lpr) Mice

Infiltrating leukocytes may be responsible for autoimmune disease. We hypothesized that the chemokine monocyte chemoattractant protein (MCP)-1 recruits macrophages and T cells into tissues that, in turn, are required for autoimmune disease. Using the MRL-Fas(lpr) strain with spontaneous, fatal autoi...

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Detalles Bibliográficos
Autores principales: Tesch, Gregory H., Maifert, Stefanie, Schwarting, Andreas, Rollins, Barrett J., Kelley, Vicki Rubin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195716/
https://www.ncbi.nlm.nih.gov/pubmed/10601356