The Selection of M3-Restricted T Cells Is Dependent on M3 Expression and Presentation of N-Formylated Peptides in the Thymus

The major histocompatibility complex (MHC) class Ib molecule H2-M3 binds N-formylated peptides from mitochondria and bacteria. To explore the role of M3 expression and peptide supply in positive and negative selection, we generated transgenic mice expressing an M3-restricted TCR-α/β from a CD8(+) T...

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Detalles Bibliográficos
Autores principales: Chiu, Nancy M., Wang, Bin, Kerksiek, Kristen M., Kurlander, Roger, Pamer, Eric G., Wang, Chyung-Ru
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195718/
https://www.ncbi.nlm.nih.gov/pubmed/10601361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195718/
https://www.ncbi.nlm.nih.gov/pubmed/10601361

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