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Partially Phosphorylated T Cell Receptor ζ Molecules Can Inhibit T Cell Activation

The T cell receptor complex (TCR) ζ chain is constitutively tyrosine phosphorylated specifically at two of the six ζ immunoreceptor tyrosine-based activation motif (ITAM) tyrosine residues in resting peripheral T cells. Further phosphorylation of ζ is induced by both agonist and antagonist ligands o...

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Detalles Bibliográficos
Autores principales: Kersh, Ellen N., Kersh, Gilbert J., Allen, Paul M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195733/
https://www.ncbi.nlm.nih.gov/pubmed/10587353