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A Single Amino Acid Determines the Immunostimulatory Activity of Interleukin 10

Cellular interleukin 10s (cIL-10s) of human and murine origin have extensive sequence and structural homology to the Epstein-Barr virus BCRF-I gene product, known as viral IL-10 (vIL-10). Although these cytokines share many immunosuppressive properties, vIL-10 lacks several of the immunostimulatory...

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Detalles Bibliográficos
Autores principales: Ding, Yaozhong, Qin, Lihui, Kotenko, Serguei V., Pestka, Sidney, Bromberg, Jonathan S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195749/
https://www.ncbi.nlm.nih.gov/pubmed/10637267