Critical Role for Cd8 in T Cell Receptor Binding and Activation by Peptide/Major Histocompatibility Complex Multimers

Recent data using MHC/peptide tetramers and dimers suggests that the T cell coreceptors, CD4 and CD8, although important for T cell activation, do not play a direct role in facilitating T cell receptor (TCR) binding to multivalent MHC/peptide ligands. Instead, a current model proposes that corecepto...

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Detalles Bibliográficos
Autores principales: Daniels, Mark A., Jameson, Stephen C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195759/
https://www.ncbi.nlm.nih.gov/pubmed/10637277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195759/
https://www.ncbi.nlm.nih.gov/pubmed/10637277

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