Activation of Nuclear Factor κb and bcl-x Survival Gene Expression by Nerve Growth Factor Requires Tyrosine Phosphorylation of IκBα

NGF has been shown to support neuron survival by activating the transcription factor nuclear factor-κB (NFκB). We investigated the effect of NGF on the expression of Bcl-xL, an anti–apoptotic Bcl-2 family protein. Treatment of rat pheochromocytoma PC12 cells, human neuroblastoma SH-SY5Y cells, or pr...

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Detalles Bibliográficos
Autores principales: Bui, Nguyen Truc, Livolsi, Antonia, Peyron, Jean-Francois, Prehn, Jochen H.M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195773/
https://www.ncbi.nlm.nih.gov/pubmed/11266466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195773/
https://www.ncbi.nlm.nih.gov/pubmed/11266466

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