The Src Homology 2 Domain of Vav Is Required for Its Compartmentation to the Plasma Membrane and Activation of C-Jun Nh(2)-Terminal Kinase 1

Vav is a hematopoietic cell–specific guanine nucleotide exchange factor (GEF) whose activation is mediated by receptor engagement. The relationship of Vav localization to its function is presently unclear. We found that Vav redistributes to the plasma membrane in response to Fc∈ receptor I (Fc∈RI) e...

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Detalles Bibliográficos
Autores principales: Arudchandran, Ramachandran, Brown, Martin J., Peirce, Matthew J., Song, James S., Zhang, Juan, Siraganian, Reuben P., Blank, Ulrich, Rivera, Juan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195799/
https://www.ncbi.nlm.nih.gov/pubmed/10620604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195799/
https://www.ncbi.nlm.nih.gov/pubmed/10620604

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