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Differential Roles of Interleukin 15 mRNA Isoforms Generated by Alternative Splicing in Immune Responses in Vivo

At least two types of interleukin (IL)-15 mRNA isoforms are generated by alternative splicing at the 5′ upstream of exon 5 in mice. To elucidate the potential roles of IL-15 isoforms in immune responses in vivo, we constructed two groups of transgenic mice using originally described IL-15 cDNA with...

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Detalles Bibliográficos
Autores principales: Nishimura, Hitoshi, Yajima, Toshiki, Naiki, Yoshikazu, Tsunobuchi, Hironaka, Umemura, Masayuki, Itano, Keiko, Matsuguchi, Tetsuya, Suzuki, Misao, Ohashi, Pamela S., Yoshikai, Yasunobu
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195806/
https://www.ncbi.nlm.nih.gov/pubmed/10620614