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Expression Cloning of an Immunodominant Family of Mycobacterium tuberculosis Antigens Using Human Cd4(+) T Cells

Development of a subunit vaccine for Mycobacterium tuberculosis (Mtb) is likely to be dependent on the identification of T cell antigens that induce strong proliferation and interferon γ production from healthy purified protein derivative (PPD)(+) donors. We have developed a sensitive and rapid tech...

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Detalles Bibliográficos
Autores principales: Alderson, Mark R., Bement, Teresa, Day, Craig H., Zhu, Liqing, Molesh, David, Skeiky, Yasir A. W., Coler, Rhea, Lewinsohn, David M., Reed, Steven G., Dillon, Davin C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195809/
https://www.ncbi.nlm.nih.gov/pubmed/10662800