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Cd40-Independent Pathways of T Cell Help for Priming of Cd8(+) Cytotoxic T Lymphocytes

In many cases, induction of CD8(+) CTL responses requires CD4(+) T cell help. Recently, it has been shown that a dominant pathway of CD4(+) help is via antigen-presenting cell (APC) activation through engagement of CD40 by CD40 ligand on CD4(+) T cells. To further study this three cell interaction,...

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Detalles Bibliográficos
Autores principales: Lu, Zhengbin, Yuan, Lingxian, Zhou, Xianzheng, Sotomayor, Eduardo, Levitsky, Hyam I., Pardoll, Drew M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195823/
https://www.ncbi.nlm.nih.gov/pubmed/10662799