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Src-like Adaptor Protein (Slap) Is a Negative Regulator of T Cell Receptor Signaling

Initiation of T cell antigen receptor (TCR) signaling is dependent on Lck, a Src family kinase. The Src-like adaptor protein (SLAP) contains Src homology (SH)3 and SH2 domains, which are highly homologous to those of Lck and other Src family members. Because of the structural similarity between Lck...

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Detalles Bibliográficos
Autores principales: Sosinowski, Tomasz, Pandey, Akhilesh, Dixit, Vishva M., Weiss, Arthur
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195826/
https://www.ncbi.nlm.nih.gov/pubmed/10662792