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Lck Domains Differentially Contribute to Pre–T Cell Receptor (Tcr)–And TCR-α/β–Regulated Developmental Transitions

Maturational changes at the CD4(−)CD8(−) double negative (DN) to CD4(+)CD8(+) double positive (DP) transition are dependent on signals generated via the pre–T cell receptor (TCR) and the nonreceptor protein tyrosine kinase p56(lck) (Lck). How Lck activities are stimulated or relayed after pre-TCR fo...

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Detalles Bibliográficos
Autores principales: Lin, Kui, Longo, Nancy S., Wang, Xin, Hewitt, Judy A., Abraham, Kristin M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195836/
https://www.ncbi.nlm.nih.gov/pubmed/10684862