T Cell Receptor Complementarity Determining Region 3 Length Analysis Reveals the Absence of a Characteristic Public T Cell Repertoire in Neonatal Tolerance: The Response in the “Tolerant” Mouse within the Residual Repertoire Is Quantitatively Similar but Qualitatively Different

All adult BALB/c mice immunized with hen egg white lysozyme (HEL) or its dominant determinant, peptide (p)106–116, mount a T cell response using a “public” Vβ8.2Jβ1.5 T cell clone. Neonatal exposure to tolerance-inducing doses of antigen can drastically diminish responsiveness in the draining lymph...

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Detalles Bibliográficos
Autores principales: Maverakis, Emanual, Beech, Jonathan T., Wilson, Stephen S., Quinn, Anthony, Pedersen, Brian, Sercarz, Eli E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195845/
https://www.ncbi.nlm.nih.gov/pubmed/10684861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195845/
https://www.ncbi.nlm.nih.gov/pubmed/10684861

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