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Fcγ Receptor Iib–Deficient Mice Develop Goodpasture's Syndrome upon Immunization with Type IV Collagen: A Novel Murine Model for Autoimmune Glomerular Basement Membrane Disease

The combination of hemorrhagic pneumonitis and rapidly progressive glomerulonephritis is a characteristic feature of Goodpasture's syndrome (GPS), an autoimmune disease resulting from the interaction of pathogenic anti–collagen type IV (C-IV) antibodies with alveolar and glomerular basement mem...

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Detalles Bibliográficos
Autores principales: Nakamura, Akira, Yuasa, Takae, Ujike, Azusa, Ono, Masao, Nukiwa, Toshihiro, Ravetch, Jeffrey V., Takai, Toshiyuki
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195851/
https://www.ncbi.nlm.nih.gov/pubmed/10704470