High Frequency of Autoreactive Myelin Proteolipid Protein–Specific T Cells in the Periphery of Naive Mice: Mechanisms of Selection of the Self-Reactive Repertoire

The autoreactive T cells that escape central tolerance and form the peripheral self-reactive repertoire determine both susceptibility to autoimmune disease and the epitope dominance of a specific autoantigen. SJL (H-2(s)) mice are highly susceptible to the induction of experimental autoimmune enceph...

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Detalles Bibliográficos
Autores principales: Anderson, Ana C., Nicholson, Lindsay B., Legge, Kevin L., Turchin, Vadim, Zaghouani, Habib, Kuchroo, Vijay K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195861/
https://www.ncbi.nlm.nih.gov/pubmed/10704458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195861/
https://www.ncbi.nlm.nih.gov/pubmed/10704458

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